“20-percent doctor included” & Dr. Algorithm: Speculations and musings of a technology optimist

Healthcare has a radical opportunity to reinvent itself. Healthcare today often results in suboptimal patient outcomes despite doctors doing the best they can within the current system. Suboptimal outcomes result from the incomplete knowledge and personal biases of today’s system. Medicine has historically been approached according to tradition – the experiential evolution of best practices, and a reductionist system of small trials. Optimal treatment outcomes require a healthcare system that is instead primed by holistic, scientifically, probabilistically or other statistically-validated data and conclusions presented to patients as cost/benefit choices. It is time to move beyond the stethoscope, which remains the iconic diagnostic tool for most healthcare professionals worldwide, 200 years after its invention.
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Consumer fundraising checklist

So, you’re trying to raise money. Here’s a guide for thinking about the kind of information you’ll need to craft a narrative about your company. Depending on your stage of growth, you may want to focus on different elements of this checklist. This is meant as a general guide, not a prescriptive template. Read More



The art, science, and labor of recruiting

Congratulations, you are now an executive at a venture-backed company! You survived the presentations, the term sheet shuffle and the due-diligence. Everyone is calling you the Founder (which is true), yet you are actually a technologist, an engineer or just a “great ideas person” with an instinct for the market. But now you have to recruit a team; perhaps, for example, a VP Marketing (maybe you have never been in a room with a real VP Marketing and don't really know what one does or how to assess his or her capabilities!) Worse still, you might be recruiting a CEO but have never really understood what a CEO does or how to appraise one. How do you evaluate a candidate, especially for a management role that you do not have great familiarity with? Read More




If/then planning

The goal of if/then scenario planning is to better understand how you can manage your company’s spend and ensure capital efficiency in order to achieve success. Ask yourself what bad things could happen, and what would your countermeasures be? Read More


Forbes / The big green opportunity: Transforming clean tech into “main tech”

Clean tech as we see it continues to be a large opportunity – one that we believe will create significant impact and positive returns – despite what the pundits are saying. Clean tech as we see it continues to be a large opportunity – one that we believe will create significant impact and positive returns – despite what the pundits are saying. Read More


Gene pool engineering for entrepreneurs: Benefits of gene pool engineering (5/11)

The goal of startups is to create products that disrupt an established industry with its own rules and product lines. To ensure this, the founders require diversity in their team. Not diversity in the generic sense, but diversity in specific dimensions: age, professional record, academic background, and mindset. This risk-tuned diversity manifests in the product through the reduction of time, energy and resources to achieve the first key iterations. Read More


Gene pool engineering for entrepreneurs: Step #1: Identify the five largest risks (6/11)

Systematically identify risky components and their multiple failure modes. Risks fall into the category of technical risk, where the failure of interdependent modules could result in the collapse of the product as a whole or general business risk or marketing risk, which encompasses everything else that is required to take the product to market. Read More